Thiolated Cyclodextrin: Development of a Mucoadhesive Vaginal Delivery System for Acyclovir. - May 2016
The objective of this study was the development of a mucoadhesive vaginal delivery system for acyclovir (Acv). Sodium-per-iodate (NaIO4) was used to introduce aldehyde substructures into beta-cyclodextrin (β-CD) by oxidative cleavage of vicinal diol bonds. Cysteamine was covalently attached to β-CD-
Schizophrenia therapy options increasing. - September 2014
New medications may soon offer more effective treatments for the approximately 2.5 million patients globally with schizophrenia. Current therapies in 2012 yielded $5.2 billion in global market sales, but by 2022 that is expected to reach $7.9 billion.
Modest growth seen in epilepsy market. - November 2014
The epilepsy market's $4.2 billion in global sales in 2012 is expected to increase to $5.4 billion by 2022. In a market crowded with products, pharmaceutical companies have shifted their focus to devising safe adjunctive therapies for refractory patients.
Diabetes market grows ever more crowded. - December 2014
Global prevalence of type-2 diabetes is expected to reach 330 million cases by 2022, with medication sales of $67.7 billion. The market is crowded with generic medications, and most products now in the development pipeline are "me-too" drugs.
Steady progress on Parkinson's disease. - October 2014
Treatment of Parkinson's disease is expected to lead to $3.56 billion in global sales in 2022. Manufacturers are reformulating medications in addition to creating new ones.
Electrospun formulations of acyclovir, ciprofloxacin and cyanocobalamin for ocular drug delivery. - April 2016
Two series of fibers containing the active ingredients acyclovir, ciprofloxacin and cyanocobalamin, and combinations of these drugs, were prepared by electrospinning. One set used the hydrophilic poly(vinylpyrrolidone) (PVP) as the filament-forming polymer, while the other used the slow-dissolving p
HTM 2022 medical gas pipeline systems. - February 1995
The new edition of HTM 2022 was published in April 1994 and supersedes HTM 22 which was last published in 1978. The new HTM was prepared following extensive consultation within the NHS and with contractors, manufacturers and other health care professionals. This article summarises the significant changes and developments which have been incorporated into the new HTM 2022. These developments are operational and technical and have considerable implications for Estates Managers. There are many sign...
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